Our paper on miRNA target prediction has been accepted by Genome Biology. In this study, we combined miRNA binding and target expression profiling data to develop an improved model for target prediction. Weijun is the first author on this study.
Holly is a visiting PhD student from Harbin Medical University. She will explore the roles of miRNAs and extracellular vesicles in cancer development.
Cindy completed her PhD in bioinformatics at Harbin Medical University, China. She previously studied on human endogenous retrovirus involving in autoimmune disease and the relationships between small molecules and miRNAs. Her project here will be focused on bioinformatics and miRNA biomarkers in...
Gongyu is a first-year PhD student in the Department of Mechanical Engineering. He completed his master program in 2017 and now starts his PhD study on bioinformatics analysis in our lab.
Pippa Cosper has completed her residency training at WashU, including a Holman Pathway fellowship in our lab on translational cancer research. She is now a clinical instructor and Bentson Fellow at University of Wisconsin. In her new position, Pippa will continue to work on clinical and translati...
Nathan Wong accepts his position as Bioinformatics Analyst with Leidos Biomedical in Frederick, Maryland. Congratulations and wish you a bright future!
We received an NIH grant to develop novel methods to further improve the CRISPR/Cas9 knockout technology.
Himanshi completed her PhD in molecular biology from CSIR-IGIB, situated in New Delhi, India. Her thesis was focused the mechanistic role of microRNAs in metabolic disease development.
Tony received his B.S. in Applied Mathematics from Johns Hopkins University. He will graduate from WUSTL’s post-bacc premed program in May 2018.
Congratulations, Dr. Wong!
Christian is a first-year PhD student from the DBBS MCB program. His rotation project is about miRNAs and extracellular vesicles.
Arlise received her PhD in biology from Northwestern University. Her thesis was focused on studying mechanisms in RNA-mediated gene silencing.
Nathan’s OncomiR paper has been accepted by Bioinformatics. OncomiR is a newly developed online resource for exploring miRNA dysregulation in cancer. OncomiR website: http://www.oncomir.org/
Pippa presented her research at the annual meeting of the American Society for Therapeutic Radiology and Oncology in San Diego, CA. She gave an oral presentation on her work, “Maintenance of HPV Gene Expression and Decreased Local Immune Response during Chemoradiation are Associated with De...
Yuhao is a first-year PhD student in Department of Electrical and System Engineering. He just completed his master thesis in our lab this summer and now continues his PhD study on bioinformatics analysis of miRNAs.
We bid farewell to Paul, who has played a leading role in developing cutting-edge CRISPR and miRNA technologies in the lab. Paul will start his new job as a Specialist at Clonetech, a Takara Bio company.
We have received a five-year (2017-2022) NIH R01 grant to study miRNA biomarkers in head and neck cancer. We will perform both expression profiling and computational analysis to identify cancer biomarkers. This new grant will greatly speed up our long-term efforts in translational cancer research.
A warm welcome to Ping. Ping has many years of research experience in molecular and cell biology.
We bid farewell to Shuai, who was a postdoc in the lab working on bioinformatics and genomics analysis. Shuai will start his new job as a Bioinformatics Scientist at OmicSoft, a Qiagen company. Best wishes to his new endeavor at Qiagen.
Weijun’s paper on functional characterization of miR-126 in kidney cancer is published in Cancer Letters. Hanxiang is a co-first author on the paper. This study shows that miR-126 plays a tumor suppressor role in clear cell renal cell carcinoma, and deactivation of miR-126 induces hypoxia l...
Yuhao is a master student in Department of Electrical and System Engineering. He will complete his master thesis in our lab this year and continue his PhD study later.
We bid farewell to Hanxiang, who joined the lab in December 2014 as a visiting student from Shandong University in China. He has completed his training in our lab and is now transferring back to Shandong University to defend his PhD thesis in the fall of 2017.
Congratulations to Nathan and his wife, Amy, on their newborn daughter, Adelaide Marion, and their son, Richard, on becoming a big brother! See the full post for the happy brother and sister.
Nathan received a travel grant to present his research at the annual conference of the Biomedical Engineering Society in Minneapolis, MN. His poster is titled, “Applications of The Cancer Genome Atlas for the Identification of RNA-Based Prognostic Biomarkers and Signatures.”
Shariq’s paper on HPV biomarkers in head and neck is published by Int J Radiat Oncol Biol Phys. This study shows that high HPV E6 expression is a prognostic biomarker that can be used to predict metastasis and poor survival in oropharyngeal cancer. This finding provides a new strategy to id...
Nathan’s paper on identifying miRNA biomarkers in head and neck cancers is published in Cancer Medicine. In this study, a robust 4-miRNA prognostic signature for oropharyngeal cancer, a major subtype of head and neck cancer, was developed using sequencing data from The Cancer Genome Atlas (...
Our NIH R01 grant on combined computational and experimental analyses of miRNA targets was successfully renewed for another four years (2016-2020). We are delighted that our previous work was well recognized by the grant reviewers, who gave our grant an impressive score of 2nd percentile.
Shariq has accepted an Assistant Professor position at Memorial Hermann Cancer Center / University of Texas Health Science Center at Houston. He will continue to do exciting translational cancer research there. Congratulations!
Pippa has been awarded a one-year research grant from the Radiological Society of North America. This will help Pippa to continue her ongoing research on identifying molecular biomarkers for cervical cancer. Congrats to Pippa!
Our new algorithm on miRNA target prediction is published in Bioinformatics. In this study, we present an improved target prediction algorithm, which was developed by modeling high-throughput profiling data from recent CLIPL (crosslinking and immunoprecipitation followed by RNA ligation) sequenci...